KEGG   Homo sapiens (human): 7867
Entry
7867              CDS       T01001                                 
Symbol
MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MDPT3, MK-3, MK3
Name
(RefSeq) MAPK activated protein kinase 3
  KO
K04444  mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04370  VEGF signaling pathway
Disease
H01890  Pattern dystrophies of the retinal pigment epithelium
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    7867 (MAPKAPK3)
   04370 VEGF signaling pathway
    7867 (MAPKAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    7867 (MAPKAPK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     7867 (MAPKAPK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  MAPKAPK family [OT]
   7867 (MAPKAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal
Other DBs
NCBI-GeneID: 7867
NCBI-ProteinID: NP_001230854
OMIM: 602130
HGNC: 6888
Ensembl: ENSG00000114738
UniProt: Q16644
Structure
Position
3:50611520..50649291
AA seq 382 aa
MDGETAEEQGGPVPPPVAPGGPGLGGAPGGRREPKKYAVTDDYQLSKQVLGLGVNGKVLE
CFHRRTGQKCALKLLYDSPKARQEVDHHWQASGGPHIVCILDVYENMHHGKRCLLIIMEC
MEGGELFSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSHNIAHRDVKPENLLYTSKEKD
AVLKLTDFGFAKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFP
PFYSNTGQAISPGMKRRIRLGQYGFPNPEWSEVSEDAKQLIRLLLKTDPTERLTITQFMN
HPWINQSMVVPQTPLHTARVLQEDKDHWDEVKEEMTSALATMRVDYDQVKIKDLKTSNNR
LLNKRRKKQAGSSSASQGCNNQ
NT seq 1149 nt   +upstreamnt  +downstreamnt
atggatggtgaaacagcagaggagcaggggggccctgtgcccccgccagttgcacccggc
ggacccggcttgggcggtgctccgggggggcggcgggagcccaagaagtacgcagtgacc
gacgactaccagttgtccaagcaggtgctgggcctgggtgtgaacggcaaagtgctggag
tgcttccatcggcgcactggacagaagtgtgccctgaagctcctgtatgacagccccaag
gcccggcaggaggtagaccatcactggcaggcttctggcggcccccatattgtctgcatc
ctggatgtgtatgagaacatgcaccatggcaagcgctgtctcctcatcatcatggaatgc
atggaaggtggtgagttgttcagcaggattcaggagcgtggcgaccaggctttcactgag
agagaagctgcagagataatgcgggatattggcactgccatccagtttctgcacagccat
aacattgcccaccgagatgtcaagcctgaaaacctactctacacatctaaggagaaagac
gcagtgcttaagctcaccgattttggctttgctaaggagaccacccaaaatgccctgcag
acaccctgctatactccctattatgtggcccctgaggtcctgggtccagagaagtatgac
aagtcatgtgacatgtggtccctgggtgtcatcatgtacatcctcctttgtggcttccca
cccttctactccaacacgggccaggccatctccccggggatgaagaggaggattcgcctg
ggccagtacggcttccccaatcctgagtggtcagaagtctctgaggatgccaagcagctg
atccgcctcctgttgaagacagaccccacagagaggctgaccatcactcagttcatgaac
cacccctggatcaaccaatcgatggtagtgccacagaccccactccacacggcccgagtg
ctgcaggaggacaaagaccactgggacgaagtcaaggaggagatgaccagtgccttggcc
actatgcgggtagactacgaccaggtgaagatcaaggacctgaagacctctaacaaccgg
ctcctcaacaagaggagaaaaaagcaggcaggcagctcctctgcctcacagggctgcaac
aaccagtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (37)   
   RefSeq(nuc) (11)   
   GenBank (13)   
   EMBL (13)   
3D Structure (5)   
   PDB (5)   
Protein domain (4)   
   Pfam (4)   
All databases (90)   

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